SMARCB1

Across TCGA patient cohorts, SMARCB1 RNA expression is significantly associated with the RNA expression of many other genes, with 18,954 significant associations in total. ACC shows the largest number of these associations.

The most reproducible SMARCB1-associated genes across cancer lineages are HIRA, RHBDD3, and SNRPD3. Each is linked with SMARCB1 in more than 32 cancer types. Because this analysis shows association rather than direction, both SMARCB1-to-partner and partner-to-SMARCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCB1 versus HIRA in ACC, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCB1→partner) and Y-score (partner→SMARCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	HIRA →	+1.111	+1.026	<.001	<.001	3	33
ACC	RHBDD3 →	+1.197	+0.938	<.001	<.001	3	33
ACC	SNRPD3 →	+1.123	+1.195	<.001	<.001	3	33
ACC	DRG1 →	+1.155	+1.192	<.001	<.001	3	33
ACC	UBE2L3 →	+1.157	+1.232	<.001	<.001	3	33
ACC	ESS2 →	+0.770	+0.925	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,954 associations by consensus.

SMARCB1 vs HIRA — ACC

Explore this scatter interactively →