SMARCB1

Across TCGA cell cohorts, SMARCB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,326 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMARCB1-associated GO terms across cancer lineages are Viral RNA genome replication, Regulation of glucose mediated signaling pathway, and Positive regulation of glucose mediated signaling pathway. Each is linked with SMARCB1 in more than 18 cancer types. Because this analysis shows association rather than direction, both SMARCB1-to-partner and partner-to-SMARCB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral RNA genome replication grouped by SMARCB1-low versus SMARCB1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCB1→partner) and Y-score (partner→SMARCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Viral RNA genome replication →	+0.184	+1.653	<.001	<.001	3	19
SOFT_TISSUE	Regulation of glucose mediated signaling pathway →	+0.171	+2.403	<.001	<.001	3	16
SOFT_TISSUE	Positive regulation of glucose mediated signaling pathway →	+0.171	+2.403	<.001	<.001	3	16
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.171	+0.981	<.001	<.001	2	17
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.171	+0.981	<.001	<.001	2	17
BREAST	DNA replication-dependent chromatin assembly →	+0.147	+1.217	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,326 associations by consensus.

Viral RNA genome replication by SMARCB1 expression — BLOOD_Lymphoma

Explore this box plot interactively →