SMARCAL1

Across TCGA patient cohorts, SMARCAL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,207 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMARCAL1-associated proteins across cancer lineages are DIS3L2, NONO, and RNF25. Each is linked with SMARCAL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMARCAL1-to-partner and partner-to-SMARCAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCAL1 versus DIS3L2 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCAL1→partner) and Y-score (partner→SMARCAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DIS3L2 →	+0.292	+0.417	.001	.001	2	5
GBM	NONO →	+0.171	+0.148	.001	.002	3	4
LSCC	RNF25 →	+0.289	+0.504	<.001	<.001	3	4
OV	THEM6 →	-0.523	-0.636	<.001	<.001	3	4
LSCC	XRCC5 →	+0.222	+0.461	<.001	<.001	3	4
GBM	POGK →	+0.254	+0.162	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,207 associations by consensus.

SMARCAL1 vs DIS3L2 — OV

Explore this scatter interactively →