SMARCAL1

Across TCGA patient cohorts, SMARCAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,714 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMARCAL1-associated genes across cancer lineages are LANCL1, RPL37A-DT, and ATIC. Each is linked with SMARCAL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMARCAL1-to-partner and partner-to-SMARCAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCAL1 versus LANCL1 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCAL1→partner) and Y-score (partner→SMARCAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LANCL1 →	+0.635	+0.244	<.001	<.001	3	5
OV	RPL37A-DT →	+0.677	+0.289	<.001	<.001	3	5
HNSC	ATIC →	+0.619	+0.225	.009	<.001	3	4
LSCC	USP37 →	+0.443	+0.202	<.001	<.001	3	4
HNSC	STK16 →	+0.392	+0.140	<.001	<.001	3	3
HNSC	FARSB →	+0.527	+0.155	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,714 associations by consensus.

SMARCAL1 vs LANCL1 — LSCC

Explore this scatter interactively →