SMARCAD1

Across TCGA cell cohorts, SMARCAD1 mutation is significantly associated with the RNA expression of many other genes, with 641 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMARCAD1-associated genes across cancer lineages are OR4D6, NCBP2L, and OR4F6. Each is linked with SMARCAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMARCAD1-to-partner and partner-to-SMARCAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D6 grouped by SMARCAD1-low versus SMARCAD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCAD1→partner) and Y-score (partner→SMARCAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4D6 →	+0.742	+5.662	<.001	.002	3	1
BLOOD_Leukemia	NCBP2L →	+0.012	+3.234	.007	.008	3	1
BLOOD_Leukemia	OR4F6 →	+0.015	+3.922	<.001	.002	3	1
BLOOD_Leukemia	PRR30 →	+0.017	+3.684	<.001	.004	3	1
BLOOD_Leukemia	OR6N1 →	+0.181	+3.475	<.001	.006	3	1
BLOOD_Leukemia	DPRX →	+0.076	+3.475	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 641 associations by consensus.

OR4D6 by SMARCAD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →