SMARCA2

Across TCGA cell cohorts, SMARCA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,448 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SMARCA2-associated GO terms across cancer lineages are Notochord development, Positive regulation of mitochondrial membrane potential, and Response to acid chemical. Each is linked with SMARCA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SMARCA2-to-partner and partner-to-SMARCA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notochord development grouped by SMARCA2-low versus SMARCA2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCA2→partner) and Y-score (partner→SMARCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Notochord development →	-0.190	-2.007	<.001	.001	3	8
KIDNEY	Positive regulation of mitochondrial membrane potential →	+0.144	+1.185	.004	.006	3	7
BONE	Response to acid chemical →	+0.080	+1.585	.002	.002	3	7
BLOOD_Lymphoma	Positive regulation of cytoplasmic translation →	+0.069	+1.032	<.001	.001	3	7
CNS	Response to insulin →	+0.040	+1.122	<.001	<.001	3	7
OVARY	Response to amino acid →	+0.055	+1.715	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,448 associations by consensus.

Notochord development by SMARCA2 expression — URINARY_TRACT

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