SMARCA1

Across TCGA cell cohorts, SMARCA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,019 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMARCA1-associated GO terms across cancer lineages are Protein neddylation, Protein localization to ciliary membrane, and Host-mediated perturbation of viral process. Each is linked with SMARCA1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SMARCA1-to-partner and partner-to-SMARCA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein neddylation grouped by SMARCA1-low versus SMARCA1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCA1→partner) and Y-score (partner→SMARCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein neddylation →	+0.096	+1.218	.001	.002	2	12
BREAST	Protein localization to ciliary membrane →	+0.089	+1.495	<.001	.005	2	12
STOMACH	Host-mediated perturbation of viral process →	+0.074	+3.313	.009	<.001	3	11
LUNG_NSCLC_LUSC	Cell division →	+0.100	+2.609	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.083	+1.330	.004	.001	3	10
LUNG_NSCLC_LUSC	Regulation of organelle assembly →	+0.068	+2.342	.002	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,019 associations by consensus.

Protein neddylation by SMARCA1 expression — SKIN

Explore this box plot interactively →