SMAP2

Across TCGA cell cohorts, SMAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,707 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMAP2-associated genes across cancer lineages are C12orf57, LANCL1, and HDAC4. Each is linked with SMAP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SMAP2-to-partner and partner-to-SMAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMAP2 versus C12orf57 in BLOOD_Lymphoma, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMAP2→partner) and Y-score (partner→SMAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C12orf57 →	+1.896	+1.417	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	LANCL1 →	+1.212	+1.194	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	HDAC4 →	+1.955	+1.855	.004	.002	3	6
LUNG_SCLC	TMED9 →	-1.146	-1.548	.003	.001	3	6
BLOOD_Lymphoma	WSB2 →	+2.522	+1.806	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	DCK →	+1.263	+1.228	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,707 associations by consensus.

SMAP2 vs C12orf57 — BLOOD_Lymphoma

Explore this scatter interactively →