SMAP1

Across TCGA cell cohorts, SMAP1 mutation is significantly associated with the drug of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMAP1-associated genes across cancer lineages are 50869, Ispinesib Mesylate, and WZ3105. Each is linked with SMAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMAP1-to-partner and partner-to-SMAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 50869 grouped by SMAP1-low versus SMAP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMAP1→partner) and Y-score (partner→SMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	50869 →	+0.526	+2.649	.011	.046	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.740	+2.652	.022	.045	3	1
LARGE_INTESTINE	WZ3105 →	+0.754	+2.652	.029	.045	3	1
LARGE_INTESTINE	Tivozanib →	+0.233	+2.786	.039	.037	3	1
LARGE_INTESTINE	JAK3_7406 →	+0.445	+2.649	.030	.046	2	1
LARGE_INTESTINE	776928 →	+0.683	+2.649	.030	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

50869 by SMAP1 expression — LARGE_INTESTINE

Explore this box plot interactively →