SLX1B-SULT1A4

Across TCGA pan-cancer cohorts, SLX1B-SULT1A4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SLX1B-SULT1A4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLX1B-SULT1A4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLX1B-SULT1A4 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUAD show a favorable association.

KIRC, COAD, and DLBC are the cancer types where SLX1B-SULT1A4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.525	0.673	<.001	65	view →
COAD	DFS	Tertile	All	0.336	0.552	<.001	63	view →
DLBC	DFS	Tertile	All	0.113	0.837	<.001	50	view →
BRCA	DFS	Quartile	All	0.415	0.551	.006	42	view →
UCEC	DFS	Tertile	All	0.826	0.907	.005	42	view →
BLCA	DFS	Median	II,III,IV	0.698	0.568	.003	36	view →
KIRP	OS	Quartile	II,III,IV	0.111	0.794	<.001	30	view →
LIHC	OS	Tertile	All	0.356	0.540	.014	21	view →
ACC	DFS	Tertile	All	0.390	0.652	.042	20	view →
PRAD	DFS	Tertile	All	0.834	0.903	.020	18	view →
LUAD	OS	Tertile	III,IV	0.803	0.581	.006	16	view →
READ	OS	Quartile	II,III,IV	0.861	0.314	.014	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SLX1B-SULT1A4–KIRC (DFS)

Open the KIRC breakdown →