Across TCGA pan-cancer cohorts, SLX1A-SULT1A3 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SLX1A-SULT1A3 data layer.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SLX1A-SULT1A3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLX1A-SULT1A3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and THYM show a favorable association.
KIRP, ACC, and PRAD are the cancer types where SLX1A-SULT1A3 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.