SLTM

Across TCGA patient cohorts, SLTM protein abundance is significantly associated with the protein abundance of many other proteins, with 28,267 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLTM-associated proteins across cancer lineages are PNN, PPP1R10, and CTCF. Each is linked with SLTM in more than 9 cancer types. Because this analysis shows association rather than direction, both SLTM-to-partner and partner-to-SLTM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLTM versus PNN in GBM, with a Pearson correlation of 0.79.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLTM→partner) and Y-score (partner→SLTM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PNN →	+0.429	+0.347	<.001	<.001	3	10
GBM	PPP1R10 →	+0.382	+0.320	<.001	<.001	3	10
GBM	CTCF →	+0.411	+0.250	<.001	<.001	3	10
GBM	ZC3H4 →	+0.329	+0.318	<.001	<.001	3	10
GBM	ZNF638 →	+0.339	+0.344	<.001	<.001	3	10
GBM	SAFB →	+0.402	+0.337	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,267 associations by consensus.

SLTM vs PNN — GBM

Explore this scatter interactively →