SLPI

Across TCGA patient cohorts, SLPI RNA expression is significantly associated with the protein abundance of many other proteins, with 19,761 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SLPI-associated proteins across cancer lineages are LCN2, RALGAPA2, and C1orf116_S519. Each is linked with SLPI in more than 6 cancer types. Because this analysis shows association rather than direction, both SLPI-to-partner and partner-to-SLPI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLPI versus LCN2 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLPI→partner) and Y-score (partner→SLPI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCN2 →	+1.304	+1.730	<.001	<.001	3	7
LUAD	RALGAPA2 →	+0.352	+1.382	<.001	<.001	3	6
BRCA	C1orf116_S519 →	+1.824	+3.177	<.001	<.001	3	6
BRCA	C1orf116_T456 →	+1.170	+2.554	<.001	.001	3	6
LSCC	CAPS_S40 →	+1.357	+1.585	.001	.002	3	6
GBM	ANXA3 →	+1.144	+1.500	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,761 associations by consensus.

SLPI vs LCN2 — GBM

Explore this scatter interactively →