Across TCGA patient cohorts, SLITRK6 mutation is significantly associated with the RNA expression of many other genes, with 3,646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLITRK6-associated genes across cancer lineages are EMID1, ZNF280B, and XIAPP1. Each is linked with SLITRK6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLITRK6-to-partner and partner-to-SLITRK6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK6→partner) and Y-score (partner→SLITRK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EMID1 →	-0.841	-2.796	.005	.003	3	4
UCEC	ZNF280B →	+0.469	+1.958	<.001	<.001	3	3
KIRC	XIAPP1 →	+0.068	+2.756	<.001	.003	3	3
COAD	ECHS1 →	+0.451	+3.223	.001	.008	2	4
UCEC	RITA1 →	+0.342	+1.711	.001	.006	3	3
COAD	PSMB6 →	+0.529	+3.489	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

Exploration

SLITRK6 survival (RNA) · tumor vs normal (RNA) · all SLITRK6 data types