Across TCGA cell cohorts, SLITRK6 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLITRK6-associated genes across cancer lineages are OR2T12, PRAMEF11, and OR13C4. Each is linked with SLITRK6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLITRK6-to-partner and partner-to-SLITRK6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK6→partner) and Y-score (partner→SLITRK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR2T12 →	+0.019	+3.705	<.001	.007	3	3
LUNG_SCLC	PRAMEF11 →	+0.026	+5.029	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR13C4 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR7G2 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C3 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C2 →	+0.012	+4.887	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

Exploration

SLITRK6 survival (RNA) · tumor vs normal (RNA) · all SLITRK6 data types