SLITRK5

Across TCGA patient cohorts, SLITRK5 mutation is significantly associated with the RNA expression of many other genes, with 7,081 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLITRK5-associated genes across cancer lineages are PARP2, PAICS, and EME1. Each is linked with SLITRK5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLITRK5-to-partner and partner-to-SLITRK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PARP2 grouped by SLITRK5-low versus SLITRK5-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK5→partner) and Y-score (partner→SLITRK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PARP2 →	+0.466	+2.516	.001	.009	3	6
STAD	PAICS →	+0.542	+2.115	<.001	<.001	3	5
UCEC	EME1 →	+0.404	+1.436	<.001	<.001	3	5
STAD	OXA1L →	+0.295	+1.635	<.001	.002	3	5
UCEC	DCK →	+0.430	+1.485	.002	.002	3	5
STAD	CCNB2 →	+0.627	+3.906	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,081 associations by consensus.

PARP2 by SLITRK5 expression — LUAD

Explore this box plot interactively →