Across TCGA cell cohorts, SLITRK2 mutation is significantly associated with the RNA expression of many other genes, with 87 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLITRK2-associated genes across cancer lineages are MS4A12, LYZL4, and GIMD1. Each is linked with SLITRK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLITRK2-to-partner and partner-to-SLITRK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK2→partner) and Y-score (partner→SLITRK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MS4A12 →	+0.109	+5.312	<.001	<.001	3	2
BLOOD_Leukemia	LYZL4 →	+0.052	+2.830	<.001	<.001	3	2
BLOOD_Leukemia	GIMD1 →	+0.014	+2.304	.002	.008	3	2
BLOOD_Myeloma	HTR3A →	+0.034	+3.716	<.001	.005	3	1
BLOOD_Myeloma	LRRC15 →	+0.034	+4.321	<.001	<.001	3	1
BLOOD_Myeloma	ENTHD1 →	+0.049	+3.285	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

Exploration

SLITRK2 survival (RNA) · tumor vs normal (RNA) · all SLITRK2 data types