Across TCGA cell cohorts, SLITRK2 mutation is significantly associated with the mutation status of many other genes, with 1,980 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLITRK2-associated genes across cancer lineages are TENM1, SLC5A11, and DSCAML1. Each is linked with SLITRK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLITRK2-to-partner and partner-to-SLITRK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK2→partner) and Y-score (partner→SLITRK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TENM1 →	+2.313	+3.282	.007	.007	1	5
BLOOD_Lymphoma	SLC5A11 →	+4.969	+4.014	.008	.008	1	4
BREAST	DSCAML1 →	+3.857	+4.807	.002	.002	1	4
LARGE_INTESTINE	PCDHA13 →	+1.444	+2.718	.006	.006	1	4
CNS	ATAD2B →	+4.459	+5.277	.005	.005	1	4
CNS	LRPPRC →	+6.044	+6.044	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,980 associations by consensus.

Exploration

SLITRK2 survival (RNA) · tumor vs normal (RNA) · all SLITRK2 data types