Across TCGA cell cohorts, SLIT3 RNA expression is significantly associated with the RNA expression of many other genes, with 7,596 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLIT3-associated genes across cancer lineages are COL5A1, PMP22, and COL6A2. Each is linked with SLIT3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SLIT3-to-partner and partner-to-SLIT3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLIT3→partner) and Y-score (partner→SLIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	COL5A1 →	+4.394	+2.854	<.001	<.001	3	8
BONE	PMP22 →	+3.463	+1.946	<.001	<.001	3	7
OESOPHAGUS	COL6A2 →	+3.702	+2.872	<.001	<.001	3	7
BONE	ADAMTS2 →	+2.959	+1.943	<.001	<.001	3	7
BONE	HTRA1 →	+3.984	+2.445	<.001	<.001	3	7
BONE	PLPP4 →	+2.707	+2.662	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,596 associations by consensus.

Exploration

SLIT3 survival (RNA) · tumor vs normal (RNA) · all SLIT3 data types