SLIT3-AS1

Across TCGA pan-cancer cohorts, SLIT3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SLIT3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLIT3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLIT3-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BLCA show a favorable association.

KIRC, READ, and ESCA are the cancer types where SLIT3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.243	0.732	.001	56	view →
READ	OS	Tertile	III,IV	0.322	0.824	.001	45	view →
ESCA	DFS	Quartile	II,III,IV	0.544	0.288	.010	34	view →
CESC	OS	Tertile	III,IV	0.421	0.703	.013	30	view →
LIHC	DFS	Tertile	All	0.375	0.568	.005	27	view →
HNSC	OS	Median	III,IV	0.232	0.448	.007	26	view →
COAD	OS	Tertile	IV	0.170	0.688	<.001	18	view →
BLCA	OS	Median	II,III,IV	0.544	0.379	.015	13	view →
ACC	OS	Tertile	II,III,IV	0.655	0.886	.032	12	view →
SKCM	DFS	Tertile	All	0.262	0.178	.024	11	view →
SARC	OS	Median	All	0.584	0.394	.008	10	view →
DLBC	OS	Tertile	All	0.605	0.941	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SLIT3-AS1–KIRC (DFS)

Open the KIRC breakdown →