SLIT2

Across TCGA patient cohorts, SLIT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,202 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SLIT2-associated proteins across cancer lineages are PRKG1, SEPTIN2, and SEPTIN7. Each is linked with SLIT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLIT2-to-partner and partner-to-SLIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLIT2 versus PRKG1 in CCRCC, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLIT2→partner) and Y-score (partner→SLIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PRKG1 →	+0.601	+1.098	<.001	<.001	3	9
PDAC	SEPTIN2 →	+0.280	+0.504	<.001	<.001	3	9
PDAC	SEPTIN7 →	+0.279	+0.488	<.001	<.001	3	8
BRCA	SSC5D →	+0.802	+0.950	<.001	<.001	3	8
HNSC	CACNA2D1 →	+0.701	+0.869	<.001	<.001	3	8
COAD	COL15A1 →	+0.511	+0.659	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,202 associations by consensus.

SLIT2 vs PRKG1 — CCRCC

Explore this scatter interactively →