Across TCGA patient cohorts, SLIT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,667 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLIT1-associated proteins across cancer lineages are SEC16A_S1305, MVP, and MYEF2_S17. Each is linked with SLIT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLIT1-to-partner and partner-to-SLIT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLIT1→partner) and Y-score (partner→SLIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEC16A_S1305 →	-0.595	-0.181	<.001	<.001	3	4
GBM	MVP →	-0.660	-1.992	<.001	<.001	3	3
LSCC	MYEF2_S17 →	+0.810	+0.419	<.001	.001	3	3
GBM	MYO1E →	-0.383	-1.293	<.001	<.001	3	3
UCEC	RASA3_S809 →	+0.603	+0.381	.006	.009	3	3
GBM	PSIP1 →	+0.534	+1.577	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,667 associations by consensus.

Exploration

SLIT1 survival (RNA) · tumor vs normal (RNA) · all SLIT1 data types