SLIT1-AS1

Across TCGA pan-cancer cohorts, SLIT1-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated SLIT1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SLIT1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLIT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as STAD and LUAD show a favorable association.

ACC, DLBC, and KIRC are the cancer types where SLIT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	III,IV	0.010	0.458	<.001	63	view →
DLBC	DFS	Tertile	III,IV	0.196	0.862	.008	36	view →
KIRC	DFS	Tertile	All	0.711	0.809	.022	24	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
OV	OS	Tertile	II,III,IV	0.775	0.848	.022	18	view →
STAD	DFS	Tertile	IV	0.656	0.247	.035	18	view →
LUAD	OS	Tertile	III,IV	1.000	0.277	.039	12	view →
LGG	OS	Median	All	0.931	0.844	.001	11	view →
ESCA	DFS	Tertile	II,III,IV	0.341	0.815	.034	9	view →
THCA	DFS	Tertile	III,IV	0.845	0.947	.018	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

SLIT1-AS1–ACC (DFS)

Open the ACC breakdown →