SLFNL1

Across TCGA patient cohorts, SLFNL1 protein abundance is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SLFNL1-associated genes across cancer lineages are TOMM22, NIN, and PYGL. Each is linked with SLFNL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLFNL1-to-partner and partner-to-SLFNL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLFNL1 versus TOMM22 in LUAD, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLFNL1→partner) and Y-score (partner→SLFNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOMM22 →	+0.577	+0.765	.002	.004	3	1
LUAD	NIN →	+0.337	+0.634	.009	.008	3	1
LUAD	PYGL →	+1.681	+0.638	.001	.009	3	1
LUAD	GSKIP →	+0.516	+0.591	.001	.002	3	1
LUAD	MYLK2 →	+0.306	+0.652	<.001	<.001	3	1
LUAD	LILRB5 →	+0.666	+0.837	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

SLFNL1 vs TOMM22 — LUAD

Explore this scatter interactively →