SLFNL1

Across TCGA cell cohorts, SLFNL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,337 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLFNL1-associated GO terms across cancer lineages are Microtubule nucleation, RISC complex assembly, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with SLFNL1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SLFNL1-to-partner and partner-to-SLFNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by SLFNL1-low versus SLFNL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLFNL1→partner) and Y-score (partner→SLFNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule nucleation →	+0.157	+0.512	<.001	<.001	3	16
BREAST	RISC complex assembly →	+0.126	+0.554	<.001	<.001	3	16
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.170	+0.481	<.001	<.001	3	15
BONE	Telomere organization →	+0.084	+0.414	<.001	.001	3	15
BLOOD_Lymphoma	Protein localization to chromosome →	+0.096	+0.562	<.001	<.001	3	15
BONE	Telomere maintenance →	+0.075	+0.382	.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,337 associations by consensus.

Microtubule nucleation by SLFNL1 expression — BONE

Explore this box plot interactively →