SLFN13

Across TCGA patient cohorts, SLFN13 protein abundance is significantly associated with the RNA expression of many other genes, with 2,450 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLFN13-associated genes across cancer lineages are PIGW, EIF3L, and ZNF436. Each is linked with SLFN13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLFN13-to-partner and partner-to-SLFN13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLFN13 versus PIGW in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLFN13→partner) and Y-score (partner→SLFN13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIGW →	+0.506	+0.513	.005	.003	3	3
PDAC	EIF3L →	-0.348	-0.296	.004	.004	3	2
UCEC	ZNF436 →	-0.645	-0.756	.001	.005	3	2
UCEC	FUCA1 →	-1.187	-1.029	.001	<.001	3	2
PDAC	C9orf163 →	+0.420	+0.229	.009	.002	3	2
UCEC	HRH2 →	+0.828	+0.906	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,450 associations by consensus.

SLFN13 vs PIGW — LSCC

Explore this scatter interactively →