SLFN12L

Across TCGA patient cohorts, SLFN12L RNA expression is significantly associated with the protein abundance of many other proteins, with 12,071 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLFN12L-associated proteins across cancer lineages are RCSD1, CORO1A, and DOCK2. Each is linked with SLFN12L in more than 9 cancer types. Because this analysis shows association rather than direction, both SLFN12L-to-partner and partner-to-SLFN12L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLFN12L versus RCSD1 in HNSC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLFN12L→partner) and Y-score (partner→SLFN12L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCSD1 →	+0.628	+0.411	<.001	<.001	3	10
HNSC	CORO1A →	+0.559	+0.402	<.001	<.001	3	10
OV	DOCK2 →	+0.576	+0.101	<.001	<.001	3	10
HNSC	DOCK8 →	+0.520	+0.431	<.001	<.001	3	10
HNSC	ABI3 →	+0.474	+0.412	<.001	<.001	3	10
HNSC	HCLS1 →	+0.595	+0.486	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,071 associations by consensus.

SLFN12L vs RCSD1 — HNSC

Explore this scatter interactively →