Across TCGA cell cohorts, SLCO6A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 672 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLCO6A1-associated GO terms across cancer lineages are Cytoplasmic translation, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with SLCO6A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLCO6A1-to-partner and partner-to-SLCO6A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO6A1→partner) and Y-score (partner→SLCO6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.063	+0.173	<.001	.009	3	6
UPPER_AERODIGESTIVE_TRACT	Promoter clearance during DNA-templated transcription →	+0.089	+0.234	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	RNA polymerase II promoter clearance →	+0.089	+0.234	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Spliceosomal complex assembly →	+0.091	+0.257	<.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.097	+0.302	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	mRNA cis splicing, via spliceosome →	+0.059	+0.173	.003	.009	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 672 associations by consensus.

Exploration

SLCO6A1 survival (RNA) · tumor vs normal (RNA) · all SLCO6A1 data types