Across TCGA cell cohorts, SLCO6A1 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLCO6A1-associated genes across cancer lineages are CCL15, LCE2C, and GLT6D1. Each is linked with SLCO6A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO6A1-to-partner and partner-to-SLCO6A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO6A1→partner) and Y-score (partner→SLCO6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCL15 →	+0.852	+3.774	<.001	.008	3	2
LUNG_NSCLC_LUAD	LCE2C →	+0.039	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	GLT6D1 →	+0.006	+5.662	<.001	.002	3	1
BLOOD_Lymphoma	CNTN6 →	+0.756	+3.295	<.001	.006	3	1
BLOOD_Lymphoma	CLCA2 →	+0.111	+3.451	.005	.008	3	1
BLOOD_Leukemia	ZP2 →	+0.102	+2.824	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

Exploration

SLCO6A1 survival (RNA) · tumor vs normal (RNA) · all SLCO6A1 data types