SLCO4C1

Across TCGA pan-cancer cohorts, SLCO4C1 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated SLCO4C1 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLCO4C1 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SLCO4C1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, ESCA, and BLCA are the cancer types where SLCO4C1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.622	.002	36	view →
ESCA	OS	Median	II,III,IV	0.164	0.702	.001	21	view →
BLCA	OS	Median	IV	0.089	0.599	<.001	15	view →
BRCA	OS	Median	III,IV	0.027	0.907	<.001	14	view →
SKCM	OS	Median	III,IV	0.214	0.728	<.001	8	view →
LUAD	DFS	Median	II,III,IV	0.178	0.721	.008	6	view →
LGG	DFS	Median	All	0.255	0.731	.002	3	view →
GBM	OS	Median	All	0.109	0.415	.032	3	view →
ACC	DFS	Median	All	0.209	0.659	.027	3	view →
SARC	DFS	Median	All	0.121	0.591	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SLCO4C1–UCEC (DFS)

Open the UCEC breakdown →