SLCO4C1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLCO4C1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,008 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SLCO4C1-associated genes across cancer lineages are ADGRE3, MEFV, and CSF3R. Each is linked with SLCO4C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO4C1-to-partner and partner-to-SLCO4C1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLCO4C1 versus ADGRE3 in PDAC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO4C1→partner) and Y-score (partner→SLCO4C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACADGRE3 →+0.765+0.943<.001<.00132
PDACMEFV →+0.788+0.921<.001<.00132
PDACCSF3R →+1.000+0.810<.001<.00132
PDACPROK2 →+0.408+0.808<.001<.00132
PDACCXCR1 →+1.173+1.230<.001<.00132
PDACCXCL5 →+1.815+0.793<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,008 associations by consensus.

SLCO4C1 vs ADGRE3 — PDAC

Per-sample scatter of SLCO4C1 vs ADGRE3 in PDAC (Pearson r = 0.60).

Explore this scatter interactively →

Exploration