SLCO4C1

Across TCGA cell cohorts, SLCO4C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,848 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLCO4C1-associated GO terms across cancer lineages are Aerobic electron transport chain, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with SLCO4C1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLCO4C1-to-partner and partner-to-SLCO4C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by SLCO4C1-low versus SLCO4C1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO4C1→partner) and Y-score (partner→SLCO4C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Aerobic electron transport chain →	+0.088	+1.012	.003	.008	3	11
LUNG_NSCLC_LUSC	ATP synthesis coupled electron transport →	+0.075	+0.414	.004	<.001	2	11
LUNG_NSCLC_LUSC	Mitochondrial ATP synthesis coupled electron transport →	+0.075	+0.414	.004	<.001	2	11
LUNG_NSCLC_LUAD	Dorsal/ventral pattern formation →	-0.072	-0.954	<.001	<.001	3	10
OESOPHAGUS	Cytoplasmic translation →	+0.095	+0.387	.001	.002	3	9
OVARY	Oxidative phosphorylation →	+0.083	+0.472	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,848 associations by consensus.

Aerobic electron transport chain by SLCO4C1 expression — LUNG_SCLC

Explore this box plot interactively →