SLCO4A1

Across TCGA pan-cancer cohorts, SLCO4A1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLCO4A1 data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLCO4A1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLCO4A1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

LUAD, COAD, and UCEC are the cancer types where SLCO4A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.109	0.750	<.001	30	view →
COAD	DFS	Median	IV	0.028	0.496	<.001	9	view →
UCEC	DFS	Median	All	0.969	0.619	.012	8	view →
BLCA	DFS	Median	III,IV	1.000	0.300	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLCO4A1–LUAD (OS)

Open the LUAD breakdown →