SLCO3A1

Across TCGA pan-cancer cohorts, SLCO3A1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLCO3A1 data layer compared with 28 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLCO3A1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLCO3A1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where SLCO3A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.661	1.000	.004	12	view →
LUAD	DFS	Quartile	All	0.895	1.000	.010	11	view →
CCRCC	OS	Tertile	III,IV	0.843	0.254	.031	4	view →
HNSC	DFS	Quartile	II,III,IV	0.974	0.829	.036	3	view →
LSCC	OS	Tertile	II,III,IV	0.861	0.567	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLCO3A1–UCEC (DFS)

Open the UCEC breakdown →