SLCO3A1

Across TCGA patient cohorts, SLCO3A1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLCO3A1-associated genes across cancer lineages are 4E-BP1, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with SLCO3A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLCO3A1-to-partner and partner-to-SLCO3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by SLCO3A1-low versus SLCO3A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO3A1→partner) and Y-score (partner→SLCO3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	4E-BP1 →	+0.310	+2.815	.010	.036	3	3
UCEC	Caspase-7-cleavedD198 →	+0.479	+2.019	.009	.005	3	2
UCEC	Cyclin-B1 →	+0.615	+2.321	<.001	.005	3	2
SKCM	Rb_pS807_S811 →	+0.480	+2.000	.013	.031	3	1
COAD	p27_pT157 →	+0.299	+2.815	<.001	.036	2	2
UCEC	14-3-3_beta →	-0.101	-2.388	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

4E-BP1 by SLCO3A1 expression — COAD

Explore this box plot interactively →