SLCO3A1

Across TCGA cell cohorts, SLCO3A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,869 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLCO3A1-associated GO terms across cancer lineages are Negative regulation of transforming growth factor beta production, Regulation of myoblast fusion, and CD8-positive, alpha-beta T cell activation. Each is linked with SLCO3A1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLCO3A1-to-partner and partner-to-SLCO3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transforming growth factor beta production grouped by SLCO3A1-low versus SLCO3A1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO3A1→partner) and Y-score (partner→SLCO3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of transforming growth factor beta production →	+0.250	+1.697	<.001	.001	3	11
STOMACH	Regulation of myoblast fusion →	+0.104	+2.272	.001	.001	3	10
CNS	CD8-positive, alpha-beta T cell activation →	+0.107	+1.488	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of protein catabolic process →	+0.072	+2.272	.004	.001	3	10
SOFT_TISSUE	Membrane protein ectodomain proteolysis →	+0.086	+1.374	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of defense response →	+0.079	+2.277	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,869 associations by consensus.

Negative regulation of transforming growth factor beta production by SLCO3A1 expression — URINARY_TRACT

Explore this box plot interactively →