SLCO2A1

Across TCGA cell cohorts, SLCO2A1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLCO2A1-associated genes across cancer lineages are CRISP1, PRAMEF15, and KRTAP13-1. Each is linked with SLCO2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO2A1-to-partner and partner-to-SLCO2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRISP1 grouped by SLCO2A1-low versus SLCO2A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO2A1→partner) and Y-score (partner→SLCO2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CRISP1 →	+0.183	+5.201	<.001	.006	3	2
OESOPHAGUS	PRAMEF15 →	+0.006	+4.906	<.001	.006	3	1
SKIN	KRTAP13-1 →	+0.032	+5.022	<.001	.002	3	1
LARGE_INTESTINE	IL17F →	+0.049	+3.029	<.001	.003	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1
LUNG_NSCLC_LUAD	CLPS →	+0.105	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

CRISP1 by SLCO2A1 expression — BLOOD_Leukemia

Explore this box plot interactively →