SLCO1C1

Across TCGA cell cohorts, SLCO1C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 523 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLCO1C1-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, U2-type prespliceosome assembly, and Positive regulation of lymphocyte apoptotic process. Each is linked with SLCO1C1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLCO1C1-to-partner and partner-to-SLCO1C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by SLCO1C1-low versus SLCO1C1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1C1→partner) and Y-score (partner→SLCO1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.113	+0.089	<.001	.006	2	5
BONE	U2-type prespliceosome assembly →	+0.112	+1.497	<.001	.002	3	4
CNS	Positive regulation of lymphocyte apoptotic process →	-0.052	-0.281	.004	.007	3	3
SOFT_TISSUE	DNA conformation change →	+0.077	+0.076	<.001	.004	3	3
BONE	Mitochondrial inner membrane fusion →	-0.087	-1.151	.009	.004	3	3
BONE	Regulation of type B pancreatic cell apoptotic process →	-0.139	-1.020	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 523 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by SLCO1C1 expression — SOFT_TISSUE

Explore this box plot interactively →