SLCO1B1

Across TCGA cell cohorts, SLCO1B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 610 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLCO1B1-associated GO terms across cancer lineages are Golgi vesicle budding, Substrate adhesion-dependent cell spreading, and Regulation of dendritic cell apoptotic process. Each is linked with SLCO1B1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLCO1B1-to-partner and partner-to-SLCO1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle budding grouped by SLCO1B1-low versus SLCO1B1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B1→partner) and Y-score (partner→SLCO1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Golgi vesicle budding →	+0.113	+0.545	.003	.005	2	5
OESOPHAGUS	Substrate adhesion-dependent cell spreading →	+0.099	+0.318	.004	.007	3	4
BLOOD_Myeloma	Regulation of dendritic cell apoptotic process →	+0.200	+0.216	.001	.007	2	5
BLOOD_Myeloma	Positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis →	+0.864	+0.213	.003	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Protein O-linked glycosylation via N-acetyl-galactosamine →	-0.065	-0.271	.005	.007	3	4
UPPER_AERODIGESTIVE_TRACT	Positive regulation of focal adhesion assembly →	+0.123	+0.424	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 610 associations by consensus.

Golgi vesicle budding by SLCO1B1 expression — STOMACH

Explore this box plot interactively →