SLC9C1

Across TCGA patient cohorts, SLC9C1 mutation is significantly associated with the RNA expression of many other genes, with 4,320 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9C1-associated genes across cancer lineages are MTND2P12, E4F1, and RNA5SP434. Each is linked with SLC9C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9C1-to-partner and partner-to-SLC9C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND2P12 grouped by SLC9C1-low versus SLC9C1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C1→partner) and Y-score (partner→SLC9C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MTND2P12 →	+0.147	+3.839	<.001	.002	3	3
UCEC	E4F1 →	+0.315	+1.470	<.001	<.001	3	3
READ	RNA5SP434 →	+0.505	+3.855	.003	.008	3	3
UCEC	NPRL2 →	+0.215	+2.439	.008	<.001	3	3
SKCM	OR5AR1 →	+0.018	+3.569	<.001	.007	3	3
LUSC	OR4H12P →	+0.142	+4.742	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,320 associations by consensus.

MTND2P12 by SLC9C1 expression — LIHC

Explore this box plot interactively →