SLC9C1

Across TCGA patient cohorts, SLC9C1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9C1-associated genes across cancer lineages are FASN, eIF4E, and Notch1. Each is linked with SLC9C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9C1-to-partner and partner-to-SLC9C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by SLC9C1-low versus SLC9C1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C1→partner) and Y-score (partner→SLC9C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.241	+1.247	.033	.041	3	3
UCEC	eIF4E →	+0.160	+1.536	.008	.002	3	2
UCEC	Notch1 →	+0.118	+1.169	.003	.017	3	2
UCEC	PCNA →	+0.247	+2.192	<.001	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.616	+2.221	<.001	<.001	3	2
UCEC	4E-BP1 →	+0.248	+2.906	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

FASN by SLC9C1 expression — UCEC

Explore this box plot interactively →