SLC9C1

Across TCGA cell cohorts, SLC9C1 mutation is significantly associated with the mutation status of many other genes, with 7,314 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9C1-associated genes across cancer lineages are ASTN2, SPATA31D1, and STAB1. Each is linked with SLC9C1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC9C1-to-partner and partner-to-SLC9C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASTN2 grouped by SLC9C1-low versus SLC9C1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C1→partner) and Y-score (partner→SLC9C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	ASTN2 →	+4.672	+4.672	.001	.001	1	7
LUNG_NSCLC_LUSC	SPATA31D1 →	+4.228	+4.228	.004	.004	1	6
SOFT_TISSUE	STAB1 →	+3.651	+4.777	.002	.002	1	6
SOFT_TISSUE	FRAS1 →	+3.329	+4.562	.003	.003	1	6
SOFT_TISSUE	IQGAP2 →	+5.066	+4.502	.007	.007	1	6
SKIN	CBX6 →	+4.906	+3.655	.001	.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,314 associations by consensus.

ASTN2 by SLC9C1 expression — URINARY_TRACT

Explore this box plot interactively →