SLC9B2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC9B2 mutation is significantly associated with the RNA expression of many other genes, with 1,599 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9B2-associated genes across cancer lineages are OSBPL9P1, RNU6-13P, and CSAG4. Each is linked with SLC9B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9B2-to-partner and partner-to-SLC9B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OSBPL9P1 grouped by SLC9B2-low versus SLC9B2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B2→partner) and Y-score (partner→SLC9B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCOSBPL9P1 →+0.019+4.757<.001.00432
LUADRNU6-13P →+0.389+4.037<.001.00432
LUADCSAG4 →+1.482+3.839<.001.00932
LUADCCNG2P1 →+0.065+4.609.008.00132
UCECSMARCE1P2 →+0.127+2.123.001<.00132
UCECTCERG1L-AS1 →+0.151+1.524.004.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,599 associations by consensus.

OSBPL9P1 by SLC9B2 expression — CESC

Box plot of OSBPL9P1 in SLC9B2-low vs SLC9B2-high samples in CESC.

Explore this box plot interactively →

Exploration