SLC9B2

Across TCGA patient cohorts, SLC9B2 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9B2-associated genes across cancer lineages are GAPDH, HER3, and Caspase-7-cleavedD198. Each is linked with SLC9B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9B2-to-partner and partner-to-SLC9B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by SLC9B2-low versus SLC9B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B2→partner) and Y-score (partner→SLC9B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.428	+2.000	.026	.030	3	2
UCEC	HER3 →	-0.237	-1.990	.016	.009	3	2
UCEC	Caspase-7-cleavedD198 →	+0.436	+2.604	.041	.005	3	2
UCEC	14-3-3_beta →	-0.074	-1.847	.041	.049	3	1
UCEC	EGFR_pY1068 →	-0.211	-2.115	.019	.017	3	1
UCEC	IGFBP2 →	-0.542	-1.874	.020	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

GAPDH by SLC9B2 expression — UCEC

Explore this box plot interactively →