SLC9B2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC9B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,276 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC9B2-associated GO terms across cancer lineages are IMP biosynthetic process, 'de novo' IMP biosynthetic process, and AMP metabolic process. Each is linked with SLC9B2 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC9B2-to-partner and partner-to-SLC9B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by SLC9B2-low versus SLC9B2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B2→partner) and Y-score (partner→SLC9B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTIMP biosynthetic process →+0.203+1.312.003.003214
LARGE_INTESTINE'de novo' IMP biosynthetic process →+0.123+1.205<.001.001312
PANCREASAMP metabolic process →+0.125+1.061<.001.004311
BLOOD_LymphomaTranscription initiation at RNA polymerase I promoter →+0.096+1.196<.001<.001311
BLOOD_LymphomaPurine nucleoside monophosphate biosynthetic process →+0.092+0.985<.001.004311
LARGE_INTESTINErRNA metabolic process →+0.076+1.287<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,276 associations by consensus.

IMP biosynthetic process by SLC9B2 expression — URINARY_TRACT

Box plot of IMP biosynthetic process in SLC9B2-low vs SLC9B2-high samples in URINARY_TRACT.

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Exploration