SLC9B2

Across TCGA cell cohorts, SLC9B2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC9B2-associated genes across cancer lineages are MMP26 and HMHB1. Each is linked with SLC9B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9B2-to-partner and partner-to-SLC9B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by SLC9B2-low versus SLC9B2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B2→partner) and Y-score (partner→SLC9B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.048	+4.217	<.001	.001	3	1
SKIN	HMHB1 →	+0.076	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MMP26 by SLC9B2 expression — LARGE_INTESTINE

Explore this box plot interactively →