SLC9B1

Across TCGA patient cohorts, SLC9B1 mutation is significantly associated with the RNA expression of many other genes, with 2,115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9B1-associated genes across cancer lineages are OR4D1, MIA-RAB4B, and SNRPCP20. Each is linked with SLC9B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9B1-to-partner and partner-to-SLC9B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D1 grouped by SLC9B1-low versus SLC9B1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B1→partner) and Y-score (partner→SLC9B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR4D1 →	+0.047	+4.254	<.001	.003	3	2
UCEC	MIA-RAB4B →	+0.059	+1.863	.003	.006	3	2
COAD	SNRPCP20 →	+0.469	+4.831	<.001	.003	3	2
BLCA	FGFR3P6 →	+0.071	+4.497	<.001	.009	3	2
SKCM	RNU6-285P →	+0.237	+4.614	<.001	.006	3	2
SKCM	KRT8P28 →	+0.048	+4.885	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,115 associations by consensus.

OR4D1 by SLC9B1 expression — SKCM

Explore this box plot interactively →