SLC9B1

Across TCGA patient cohorts, SLC9B1 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9B1-associated genes across cancer lineages are Annexin-1, EGFR_pY1068, and FoxM1. Each is linked with SLC9B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9B1-to-partner and partner-to-SLC9B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by SLC9B1-low versus SLC9B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B1→partner) and Y-score (partner→SLC9B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.606	+2.827	.013	.035	3	2
UCEC	EGFR_pY1068 →	-0.273	-2.584	.019	.011	3	1
UCEC	FoxM1 →	+0.366	+2.584	.002	.011	3	1
UCEC	INPP4B →	-0.343	-2.999	.022	.035	3	1
UCEC	JNK2 →	+0.187	+2.834	.044	.034	3	1
UCEC	Ku80 →	+0.250	+1.887	.023	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Annexin-1 by SLC9B1 expression — UCEC

Explore this box plot interactively →