SLC9A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC9A9 mutation is significantly associated with the RNA expression of many other genes, with 3,262 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A9-associated genes across cancer lineages are LSP1P3, LINC02438, and ATG101. Each is linked with SLC9A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9A9-to-partner and partner-to-SLC9A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSP1P3 grouped by SLC9A9-low versus SLC9A9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A9→partner) and Y-score (partner→SLC9A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADLSP1P3 →+0.331+3.481<.001<.00133
LUADLINC02438 →+0.730+3.284<.001.00133
UCECATG101 →+0.528+1.879<.001<.00133
SKCMLLPH →+0.379+2.497.004.00933
UCECTXNL4A →+0.385+2.705<.001<.00133
SKCMRPL23AP7 →+0.452+2.106.004.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,262 associations by consensus.

LSP1P3 by SLC9A9 expression — LUAD

Box plot of LSP1P3 in SLC9A9-low vs SLC9A9-high samples in LUAD.

Explore this box plot interactively →

Exploration