SLC9A9

Across TCGA patient cohorts, SLC9A9 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A9-associated genes across cancer lineages are ATM, 4E-BP1, and EGFR. Each is linked with SLC9A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9A9-to-partner and partner-to-SLC9A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC9A9-low versus SLC9A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A9→partner) and Y-score (partner→SLC9A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.482	-1.765	.001	.013	3	3
UCEC	4E-BP1 →	+0.277	+1.837	.001	.014	3	3
UCEC	EGFR →	-0.155	-1.459	.002	.012	3	2
UCEC	MEK1 →	+0.462	+2.000	<.001	<.001	3	2
UCEC	PDCD4 →	-0.470	-2.222	.002	.009	3	2
UCEC	Rab11 →	-0.097	-1.222	.040	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

ATM by SLC9A9 expression — UCEC

Explore this box plot interactively →